Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545045 | 1.00 | TP53 (0.58) | TP53TSHRALDH1A1RAB9ANPC1 | |
| Water SCHEMBL8461649 | 0.98 | TP53 (0.56) | TP53TSHRALDH1A1RAB9ANPC1 | |
| Water SCHEMBL8461660 | 0.98 | TP53 (0.56) | TP53TSHRALDH1A1RAB9ANPC1 | |
| SCHEMBL8459069 | 0.92 | TP53 (0.50) | TP53TSHRALDH1A1RAB9ANPC1 | |
| Water SCHEMBL8467116 | 0.89 | TP53 (0.46) | TP53TSHRALDH1A1RAB9ANPC1 | |
| SCHEMBL11229093 | 0.82 | ALDH1A1 (0.51) | TSHRALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL344758 | 0.79 | USP2 (0.55) | ALDH1A1RAB9ANPC1MAPTPOLB | |
| SCHEMBL21866481 | 0.79 | CES2 (0.52) | ALDH1A1RAB9ANPC1MAPTPOLB | |
| SCHEMBL18668782 | 0.78 | MAPT (0.48) | TP53ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL3551614 | 0.78 | TP53 (0.58) | TP53TSHRALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803962-B2 | Process for the resolution of racemic verapamil | COSMA S.P.A. (IT) | 2010-09-28 | — | — | US | disclosed |
| EP-2014644-A1 | A process for the resolution of racemic verapamil | Cosma S.p.A. (IT) | 2009-01-14 | — | — | EP | disclosed |
| US-20080306296-A1 | Process for the resolution of racemic verapamil | COSMA S.P.A | 2008-12-11 | — | — | US | disclosed |
| EP-0600714-B1 | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid | TORAY INDUSTRIES (JP) | 1999-08-18 | — | — | EP | disclosed |
| EP-0924188-A1 | Production of 0,0'-diacyltartaric acid crystals | TORAY INDUSTRIES, INC. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5451687-A | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid | TORAY INDUSTRIES, INC. (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0600714-A1 | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid | TORAY INDUSTRIES, INC. (JP) | 1994-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306296-A1 | Process for the resolution of racemic verapamil | BLVRB, RYR2, QDPR | TP53 4441/4885TSHR 4728/4885ALDH1A1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.