Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303259 | 0.80 | ALDH1A1 (0.33) | ARG1ARG2 | |
| SCHEMBL3546762 | 0.75 | EPHX1 (0.41) | — | |
| SCHEMBL15592764 | 0.75 | ARG1 (0.33) | ARG1ARG2 | |
| SCHEMBL23451474 | 0.72 | — | — | |
| SCHEMBL29184106 | 0.72 | ALDH1A1 (0.33) | ARG1ARG2 | |
| SCHEMBL3543647 | 0.72 | GABRR1 (0.33) | ARG1ARG2 | |
| SCHEMBL12269165 | 0.70 | ACACB (0.36) | ARG1ARG2 | |
| SCHEMBL5445954 | 0.69 | CA2 (0.33) | ARG1ARG2 | |
| SCHEMBL9064172 | 0.69 | — | — | |
| SCHEMBL10208075 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709471-B2 | Compounds | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20080009482-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009482-A1 | NOVEL COMPOUNDS | CYP11B2, CYP11B1, CYP46A1 | ARG1 1052/4885ARG2 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.