Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544298 | 0.80 | GLRA3 (0.32) | NOTUMRORCGLRA3GLRBASPH | |
| SCHEMBL21810001 | 0.73 | TP53 (0.43) | NOTUMMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL6988827 | 0.71 | LRRK2 (0.35) | XPO1LRRK2 | |
| SCHEMBL70872 | 0.68 | TAS2R14 (0.41) | NOTUMASPH | |
| SCHEMBL15292262 | 0.68 | LRRK2 (0.34) | LRRK2 | |
| SCHEMBL20605804 | 0.64 | MAP2K2 (0.48) | NOTUMASPH | |
| SCHEMBL841261 | 0.64 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL25985101 | 0.63 | S1PR1 (0.35) | NOTUMKDM4CKDM2BASPH | |
| Hydrochloric Acid SCHEMBL6737822 | 0.63 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL23927243 | 0.63 | ANO1 (0.39) | GLRA3GLRBASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652059-B2 | 1-methyl-4-trifluoromethyl-1H-pyrrole-3-carboxylic acid [2-(1,3-dimethylbutyl)phenyl]amide; protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | disclosed |
| US-7105565-B2 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-08-24 | — | — | US | disclosed |
| CN-1221532-C | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA PARTICIPATIONS AG (CH) | 2005-10-05 | — | — | CN | disclosed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | disclosed |
| CN-1484637-A | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | �ӳɹ� | 2004-03-24 | — | — | CN | disclosed |
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | CBR3, PYCR1, CBR1 | NOTUM 161/4885XPO1 4168/4885KDM4C 234/4885 |
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | CBR3, CTH, PYCR1 | NOTUM 262/4885XPO1 4514/4885KDM4C 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.