Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 3/20 | 0.36 |
| ▸ | CPT1A | P50416 | 3/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557319 | 0.82 | MAPK1 (0.42) | ALDH1A1HPGDMAPK1SMN1; SMN2GAA | |
| SCHEMBL3553878 | 0.80 | ALDH1A1 (0.57) | DDB1CRBNALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL28944624 | 0.80 | HTT (0.44) | HPGDMAPK1LMNASMN1; SMN2GAA | |
| SCHEMBL4399681 | 0.75 | F10 (0.56) | DDB1CRBN | |
| SCHEMBL4392508 | 0.73 | DDB1 (0.40) | DDB1CRBNOPRM1OPRL1ALDH1A1 | |
| SCHEMBL8076294 | 0.72 | DDB1 (0.47) | DDB1CRBNOPRM1ALDH1A1HPGD | |
| Hydantoin SCHEMBL3552566 | 0.72 | ALDH1A1 (0.48) | DDB1CRBNALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7257909 | 0.70 | DDB1 (0.71) | DDB1CRBNALDH1A1CYP3A4GAA | |
| SCHEMBL10814936 | 0.70 | MAPT (0.60) | DDB1CRBNALDH1A1CYP1A2ALOX5 | |
| SCHEMBL1788429 | 0.69 | MEN1 (0.58) | DDB1CRBNALDH1A1ALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645776-B2 | (R)-1-{2-[3-(4-Methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-2-phenoxy-ethanone; carnitine-dependent palmitoyltransferases (CPTs); reduce liver beta -oxidation, consequently inhibit gluconeogenesis and therefore counteract hyperglycemia | HOFFMANN-LA ROCHE INC. (US) | 2010-01-12 | — | — | US | disclosed |