SCHEMBL3553593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3553425	0.87	LMNA (0.47)	LMNASLC6A2SLC6A3KMT2ATDP1
	SCHEMBL13350445	0.84	TSHR (0.44)	LMNATDP1RAB9AALDH1A1MAPT
	SCHEMBL8536091	0.83	LMNA (0.50)	LMNASLC6A2SLC6A3KMT2ATDP1
	SCHEMBL354169	0.79	HDAC8 (0.49)	—
	SCHEMBL8533556	0.78	TAOK3 (0.45)	TDP1ALDH1A1CHRNB2CHRNA5CHRNA7
	SCHEMBL663364	0.77	KMT2A (0.55)	LMNASLC6A2SLC6A3KMT2ATDP1
	SCHEMBL8764265	0.77	MCHR1 (0.43)	KMT2ATDP1ALDH1A1MAPTHPGD
	SCHEMBL26809636	0.77	TDP1 (0.54)	LMNASLC6A2SLC6A3KMT2ATDP1
	SCHEMBL6539852	0.75	KMT2A (0.59)	LMNASLC6A2SLC6A3KMT2ATDP1
	SCHEMBL19381880	0.74	KMT2A (0.58)	LMNASLC6A2SLC6A3KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.