SCHEMBL35541

SCHEMBL35541

CCCCCCCCCCCCOC(=O)C=CC#N

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.64
ATM Q13315 1/20 0.60
NAAA Q02083 1/20 0.48
APP P05067 4/20 0.48
TSHR P16473 3/20 0.47
HPGD P15428 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
EPHX1 P07099 1/20 0.46
PRKCA P17252 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380051 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL29892 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL1452757 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL3457992 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL29341 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL15229292 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL2906298 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL2903635 1.00 HCAR2 (0.64) HCAR2ATMNAAAAPPTSHR
SCHEMBL19579380 0.98 ATM (0.63) HCAR2ATMNAAAAPPTSHR
SCHEMBL6465406 0.98 ATM (0.63) HCAR2ATMNAAAAPPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717744-A1 USE OF A COMPOSITION BASED ON CYANOACRYLATE AND (METH)ACRYLATE Bostik SA (FR) 2026-04-01 EP claimed
US-20260060402-A1 REMOVABLE NAIL COATINGS AND COMPOSITIONS AND METHODS OF PREPARING THEREOF LIQWD INC (US) 2026-03-05 US claimed
US-20250215132-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2025-07-03 US claimed
EP-4504844-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2025-02-12 EP claimed
CN-117062636-A Catheter securement compositions and methods 艾德合森生物医药有限责任公司 2023-11-14 CN claimed
WO-2023194367-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2023-10-12 WO claimed
EP-4257648-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2023-10-11 EP claimed
EP-3513744-B1 MESH DISPENSER ETHICON INC (US) 2022-11-16 EP claimed
US-11413370-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2022-08-16 US claimed
US-20200315624-A1 Flexible Material Dispenser ETHICON INC (US) 2020-10-08 US claimed
US-20030202956-A1 In situ tissue adhesive; mixture of monomer, plasticizer and stabilizer CLOSURE MEDICAL CORPORATION 2003-10-30 US claimed
US-6605667-B1 1,1-disubstituted ethylene monomers such as alpha-cyano-acrylates; storage stability CLOSURE MEDICAL CORPORATION 2003-08-12 US claimed
US-6565840-B1 Applying to abutment tissues; forming biopolymer adhesive CLOSURE MEDICAL CORPORATION 2003-05-20 US claimed
US-20030082116-A1 Adhesive compositions containing dual function stabilizers and active agents CLOSURE MEDICAL CORPORATION (US) 2003-05-01 US claimed
US-20030039781-A1 Polymeric containers for 1,1-disubstituted monomer compositions CLOSURE MEDICAL CORPORATION (US) 2003-02-27 US claimed
EP-1265851-A2 TRANSESTERIFICATION METHOD FOR MAKING CYANOACRYLATES Closure Medical Corporation (US) 2002-12-18 EP claimed
WO-2002020069-A2 ANTIOXIDANT ENRICHED ADHESIVE COMPOSITIONS AND STORAGE CONTAINERS THEREFOR CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO claimed
US-6245933-B1 CONDENSING A CYANOACETATE WITH PARAFORMALDEHYDE OR FORMALDEHYDE, REACTING THE POLYMER FORMED WITH AN ALCOHOL, AND DEPOLYMERIZING THE POLYMER TO FORM ALPHA-CYANOACRYLATE MONOMERS CLOSURE MEDICAL CORPORATION 2001-06-12 US claimed
WO-2001036380-A2 TRANSESTERIFICATION METHOD FOR MAKING CYANOACRYLATES CLOSURE MEDICAL CORPORATION (US) 2001-05-25 WO claimed
US-5981621-A COMPRISING AT LEAST ONE MONOMER, WHICH FORMS A MEDICALLY ACCEPTABLE POLYMER, AT LEAST ONE PLASTICIZING AGENT, AT LEAST ONE ACIDIC STABILIZING AGENT, AN INITIATOR CLOSURE MEDICAL CORPORATION (US) 1999-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060402-A1 REMOVABLE NAIL COATINGS AND COMPOSITIONS AND METHODS OF PREPARING THEREOF POLR1C, PRKDC, PIK3C3 HCAR2 4722/4885ATM 2853/4885NAAA 3037/4885
US-20030082116-A1 Adhesive compositions containing dual function stabilizers and active agents TLN1, PTK2, ILK HCAR2 2985/4885ATM 2978/4885NAAA 3048/4885
US-20030202956-A1 In situ tissue adhesive; mixture of monomer, plasticizer and stabilizer CAD, SMC1A, ITGA1 HCAR2 1494/4885ATM 612/4885NAAA 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.