Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 16/20 | 0.55 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558815 | 0.96 | TRPM8 (0.56) | TRPM8ALOX5PTGER1 | |
| SCHEMBL3561234 | 0.89 | ALOX5 (0.54) | TRPM8PTGESALOX5PTGER1 | |
| SCHEMBL3554230 | 0.88 | ALOX5 (0.60) | PTGESALOX5 | |
| SCHEMBL3557949 | 0.88 | ALOX5 (0.60) | PTGESALOX5 | |
| SCHEMBL3555271 | 0.88 | ALOX5 (0.59) | PTGESALOX5 | |
| SCHEMBL3556562 | 0.87 | ALOX5 (0.57) | TRPM8PTGESALOX5 | |
| SCHEMBL3555251 | 0.86 | ALOX5 (0.58) | PTGESALOX5PTGER1 | |
| SCHEMBL3553929 | 0.86 | ALOX5 (0.58) | PTGESALOX5 | |
| SCHEMBL3552963 | 0.86 | ALOX5 (0.57) | TRPM8PTGESALOX5PTGER1 | |
| SCHEMBL3554237 | 0.86 | TAS2R14 (0.57) | PTGESALOX5PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | TRPM8 3817/4885PTGES 150/4885ALOX5 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.