Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558535 | 0.92 | KDM4E (0.42) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL21816348 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL10467534 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL89040 | 0.80 | ATM (0.52) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL3560429 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL754676 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL3511611 | 0.76 | TSHR (0.57) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31214158 | 0.75 | ATM (0.47) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL6852879 | 0.75 | CA1 (0.52) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL9271076 | 0.74 | CA12 (0.48) | KDM4EALDH1A1GLAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-20060205732-A1 | Heterocyclic carboxamides and their use as fungicides | BAYER SAS (FR) | 2006-09-14 | — | — | US | disclosed |
| US-7084163-B2 | Heterocyclic carboxamides and their use as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2006-08-01 | — | — | US | disclosed |
| US-20040152698-A1 | Heterocyclic carboxamides and their use as fungicides | BAYER SAS (FR) | 2004-08-05 | — | — | US | disclosed |
| EP-1425276-A2 | HETEROCYCLIC CARBOXAMIDES AND THEIR USE AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003006454-A2 | HETEROCYCLIC CARBOXAMIDES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE S.A. (FR) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152698-A1 | Heterocyclic carboxamides and their use as fungicides | CYP1A2, CYP4X1, CYCS | KDM4E 543/4885ALDH1A1 3137/4885GLA 825/4885 |
| US-20060205732-A1 | Heterocyclic carboxamides and their use as fungicides | CYP4X1, CYP1A2, CYCS | KDM4E 501/4885ALDH1A1 2827/4885GLA 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.