Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511935 | 0.80 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL4472290 | 0.80 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL4469579 | 0.78 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL1713003 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL9794819 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL6929063 | 0.77 | ALDH1A1 (0.54) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL2228747 | 0.75 | BAZ2A (0.49) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL4463690 | 0.75 | LMNA (0.68) | SMN1; SMN2LMNAMEN1ARALDH1A1 | |
| SCHEMBL2080793 | 0.74 | OGA (0.44) | SMN1; SMN2OGAALDH1A1 | |
| SCHEMBL23155993 | 0.74 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | L3MBTL1 3267/4885SMN1; SMN2 3601/4885LMNA 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.