Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794796 | 0.93 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL3511935 | 0.84 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL4472290 | 0.84 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL4469579 | 0.82 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL1713003 | 0.81 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL6929063 | 0.81 | ALDH1A1 (0.54) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL4463690 | 0.79 | LMNA (0.68) | SMN1; SMN2LMNAMEN1ARALDH1A1 | |
| SCHEMBL2228747 | 0.79 | BAZ2A (0.49) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL23155993 | 0.78 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 | |
| SCHEMBL10136842 | 0.78 | HRH3 (0.49) | L3MBTL1SMN1; SMN2LMNAOGAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | claimed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | claimed |
| JP-1311064-A | — | — | None | — | — | JP | disclosed |
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| EP-0338352-A3 | SALICYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
| JP-H01311064-A | SALICYLIC ACID DERIVATIVES | MERCK PATENT GMBH | 1989-12-15 | — | — | JP | disclosed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |