Alpha-Thujaplicin

Alpha-Thujaplicin

SCHEMBL355646

CC(C)c1ccccc(=O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.62
GABRB2 P47870 2/20 0.62
CYP1A2 P05177 2/20 0.62
HIF1A Q16665 2/20 0.62
GABRB1 P18505 2/20 0.62
FAAH O00519 2/20 0.62
GABRG2 P18507 2/20 0.62
GABRB3 P28472 2/20 0.62
LMNA P02545 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CYP3A4 P08684 2/20 0.62
HPGD P15428 2/20 0.62
TSHR P16473 1/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
HTR2C P28335 1/20 0.62
GABRA5 P31644 1/20 0.62
GABRA3 P34903 1/20 0.62
HTR2B P41595 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hinokitiol SCHEMBL4653999 0.83 TP53 (0.70) GABRA1GABRB2CYP1A2HIF1AGABRB1
SCHEMBL23250676 0.79 GABRA1 (0.54) GABRA1GABRB2CYP1A2HIF1AGABRB1
SCHEMBL6546310 0.78 GABRA1 (0.48) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL2414429 0.78 GABRA1 (1.00) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL36245 0.78 GABRA1 (1.00) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL8935177 0.75 GABRA1 (0.94) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL5036811 0.75 GABRA1 (0.94) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL10968613 0.75 GABRA1 (0.94) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL4088686 0.75 GABRA1 (0.94) GABRA1GABRB2CYP1A2HIF1AGABRB1
Propofol SCHEMBL1033835 0.75 GABRA1 (0.94) GABRA1GABRB2CYP1A2HIF1AGABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
CN-113759026-B Common clubmoss herb and preparation characteristic map and construction method thereof 北京康仁堂药业有限公司 2023-04-07 CN claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
EP-2874664-B1 COMPOSITION FOR THERAPEUTIC USE, INCLUDING AN ORGANIC LIPID PHASE AND A RARE-EARTH RADIOISOTOPE COMPLEX CENTRE EUGENE MARQUIS (FR) 2019-06-19 EP claimed
US-9572770-B2 Stable topical composition and a process for producing a stable topical composition EVIDENCE SOLUCÕES FARMACÊUTICAS LTDA EPP (BR) 2017-02-21 US claimed
EP-2874664-A1 COMPOSITION FOR THERAPEUTIC USE, INCLUDING AN ORGANIC LIPID PHASE AND A RARE- EARTH RADIOISOTOPE COMPLEX Centre Eugene Marquis (FR) 2015-05-27 EP claimed
WO-2014012997-A1 COMPOSITION FOR THERAPEUTIC USE, INCLUDING AN ORGANIC LIPID PHASE AND A RARE- EARTH RADIOISOTOPE COMPLEX CENTRE EUGENE MARQUIS (FR) 2014-01-23 WO claimed
US-20130123220-A1 Stable Topical Composition and a Process for Producing a Stable Topical Composition EVIDENCE SOLUÇÕES FARMACÊUTICAS LTDA EPP (BR) 2013-05-16 US claimed
WO-2012009778-A2 A STABLE TOPICAL COMPOSITION AND A PROCESS FOR PRODUCING A STABLE TOPICAL COMPOSITION EVIDENCE SOLUÇÕES FARMACÊUTICAS LTDA EPP (BR) 2012-01-26 WO claimed
EP-4735568-A1 BIODEGRADABLE CHELATING AGENTS AND METHODS FOR FABRIC CARE The Procter & Gamble Company (US) 2026-05-06 EP disclosed
EP-4735567-A1 BIODEGRADABLE CHELATING AGENTS AND METHODS FOR FABRIC CARE The Procter & Gamble Company (US) 2026-05-06 EP disclosed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 US disclosed
WO-1997047289-A1 STABILIZED HINOKITIOL AND COMPOSITIONS CONTAINING SAME E-L MANAGEMENT CORPORATION (US) 1997-12-18 WO disclosed
CN-1008325-B ORAL COMPOSITION LION CORP (JP) 1990-06-13 CN disclosed
EP-0108622-B1 SYNTHETIC RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME MITSUBISHI RAYON CO., LTD. (JP) 1988-03-02 EP disclosed
CN-85109275-A ORAL COMPOSITION 1986-06-10 CN disclosed
US-4563494-A LANTHANOID COMPOUND MITSUBISHI RAYON CO., LTD. (JP) 1986-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB GABRA1 4231/4885GABRB2 2535/4885CYP1A2 3865/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT GABRA1 3154/4885GABRB2 3862/4885CYP1A2 3978/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 GABRA1 1529/4885GABRB2 1395/4885CYP1A2 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.