SCHEMBL3557557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3557974	0.95	KDM4E (0.38)	HTR6KDM4ETDP1ALDH1A1L3MBTL1
	SCHEMBL3555357	0.93	HTR6 (0.45)	HTR6KDM4ETDP1ALDH1A1SMN1; SMN2
	SCHEMBL3560859	0.93	KDM4E (0.39)	HTR6KDM4ETDP1ALDH1A1SMN1; SMN2
	SCHEMBL3562439	0.93	HTR6 (0.45)	HTR6KDM4ETDP1ALDH1A1MAPT
	SCHEMBL3566226	0.92	KDM4E (0.36)	HTR6KDM4ETDP1ALDH1A1SMN1; SMN2
	SCHEMBL3564344	0.90	HTR6 (0.39)	HTR6KDM4ETDP1ALDH1A1SMN1; SMN2
	SCHEMBL3562676	0.85	HTR6 (0.39)	HTR6KDM4ETDP1ALDH1A1SMN1; SMN2
	SCHEMBL3563475	0.85	HTR6 (0.47)	HTR6MAPTLMNAPTGDR2PSEN1
	SCHEMBL3560015	0.85	HTR6 (0.39)	HTR6KDM4EALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL3560361	0.85	HTR6 (0.38)	HTR6KDM4ETDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.