Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.65 |
| ▸ | RELA | Q04206 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 12/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489934 | 0.82 | MEN1 (0.83) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL3625738 | 0.82 | MEN1 (0.77) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL14422990 | 0.80 | MEN1 (0.82) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL2117282 | 0.79 | NPC1 (1.00) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL28663547 | 0.78 | NPC1 (0.52) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL6534828 | 0.78 | LMNA (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL903606 | 0.77 | NPC1 (0.95) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL6679319 | 0.77 | NPC1 (0.95) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL13527439 | 0.77 | NPC1 (0.95) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL6682733 | 0.77 | NPC1 (0.95) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251166-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-109251166-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-01-22 | — | — | CN | disclosed |
| US-7842825-B2 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activator | HOFFMANN-LA ROCHE INC. (US) | 2010-11-30 | — | — | US | disclosed |
| US-7700632-B2 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activator | HOFFMANN-LA ROCHE INC. (US) | 2010-04-20 | — | — | US | disclosed |
| CN-100491323-C | Biaryloxymethylarenecarboxylic acids compound | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | CN | disclosed |
| US-20080255198-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATOR | CHU CHANG AN | 2008-10-16 | — | — | US | disclosed |
| US-20080108662-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATOR | CHU CHANG A | 2008-05-08 | — | — | US | disclosed |
| US-7355049-B2 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activator | HOFFMANN-LA ROCHE INC. (US) | 2008-04-08 | — | — | US | disclosed |
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | disclosed |
| CN-1812956-A | Biaryloxymethylarenecarboxylic acids as glycogen synthase activator | HOFFMANN LA ROCHE (CH) | 2006-08-02 | — | — | CN | disclosed |
| EP-0167893-B1 | PROCESS FOR PREPARING PHOSPHORIC-ACID DERIVATIVES AND INTERMEDIATE COMPOUNDS | BAYER AG (DE) | 1988-09-14 | — | — | EP | disclosed |
| US-4769364-A | Pyrimidin-5-yl phosphoric acid ester and thionophosphoric acid ester pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-06 | — | — | US | disclosed |
| US-4769458-A | Process for the preparation of phosphoric acid derivatives and intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-06 | — | — | US | disclosed |
| EP-0167888-B1 | PROCESS FOR PREPARING PHOSPHORIC-ACID DERIVATIVES AND INTERMEDIATE COMPOUNDS | BAYER AG (DE) | 1988-08-17 | — | — | EP | disclosed |
| US-4686290-A | Preparation of pyrimidyl phosphoric acid derivatives and intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0222210-A2 | Process for preparing phosphoric-acid derivatives and intermediates | BAYER AG (DE) | 1987-05-20 | — | — | EP | disclosed |
| US-4665175-A | FROM 4-CHLORO-5-BENZYLOXYPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0167893-A1 | Process for preparing phosphoric-acid derivatives and intermediate compounds | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0167888-A1 | Process for preparing phosphoric-acid derivatives and intermediate compounds | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0128350-A2 | Pyrimidylphosphoric-acid derivatives and their use as pesticides | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108662-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATOR | GYS2, PYGL, GYS1 | NPC1 1670/4885RAB9A 4229/4885NFKB1 1049/4885 |
| US-20080255198-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATOR | GYS2, PYGL, GYS1 | NPC1 1670/4885RAB9A 4229/4885NFKB1 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.