Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Anisic Acid SCHEMBL43335 | 0.70 | CA1 (1.00) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL1157044 | 0.70 | CA1 (1.00) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL1043957 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL38654440 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL29790432 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL15548197 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL17891327 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL414716 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL846287 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 | |
| P-Anisic Acid SCHEMBL2130101 | 0.68 | CA1 (0.95) | CA1CA2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2631648-A2 | Therapeutic target for periodontal disease. | Kao Corporation (JP) | 2013-08-28 | — | — | EP | claimed |
| US-20120276546-A1 | Periodontal Disease Marker | KAO CORPORTATION (JP) | 2012-11-01 | — | — | US | claimed |
| EP-2423683-A1 | PERIODONTAL DISEASE MARKERS | Kao Corporation (JP) | 2012-02-29 | — | — | EP | claimed |
| US-20120015397-A1 | Periodontal Disease Marker (as amended herewith) | KAO CORPORATION (JP) | 2012-01-19 | — | — | US | claimed |
| EP-2631648-B1 | Therapeutic target for periodontal disease. | KAO CORP (JP) | 2015-08-12 | — | — | EP | disclosed |
| EP-2423683-B1 | Periodontal disease markers. | KAO CORP (JP) | 2015-03-18 | — | — | EP | disclosed |
| EP-2631648-A3 | Therapeutic target for periodontal disease. | Kao Corporation (JP) | 2013-12-18 | — | — | EP | disclosed |
| US-8568986-B2 | Method of selecting an agent that improves periodontal disease | KAO CORPORATION (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-2631648-A2 | Therapeutic target for periodontal disease. | Kao Corporation (JP) | 2013-08-28 | — | — | EP | disclosed |
| EP-2631648-A2 | Therapeutic target for periodontal disease. | Kao Corporation (JP) | 2013-08-28 | — | — | EP | disclosed |
| US-20120276546-A1 | Periodontal Disease Marker | KAO CORPORTATION (JP) | 2012-11-01 | — | — | US | disclosed |
| US-8293478-B2 | Method of using autoinducer-2 as a periodontal disease marker | KAO CORPORATION (JP) | 2012-10-23 | — | — | US | disclosed |
| EP-2423683-A1 | PERIODONTAL DISEASE MARKERS | Kao Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120015397-A1 | Periodontal Disease Marker (as amended herewith) | KAO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015397-A1 | Periodontal Disease Marker (as amended herewith) | IGFBP2, ORMDL3, AREG | CA1 4704/4885CA2 4063/4885POLB 4040/4885 |
| US-20120276546-A1 | Periodontal Disease Marker | IGFBP2, IL1B, F2RL1 | CA1 4674/4885CA2 3776/4885POLB 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.