SCHEMBL3560853

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6997480	0.82	LMNA (0.49)	LMNAGAAIDH1POLBALDH1A1
	SCHEMBL755692	0.81	LMNA (0.38)	LMNAGAAPOLBALDH1A1HTT
	SCHEMBL6997976	0.80	LMNA (0.47)	LMNAGAAIDH1POLBALDH1A1
	SCHEMBL2592753	0.80	LMNA (0.49)	LMNAGAAIDH1POLBALDH1A1
	SCHEMBL2115557	0.80	IDH1 (0.50)	LMNAGAAIDH1POLBALDH1A1
	SCHEMBL15910022	0.76	LMNA (0.61)	LMNAGAAIDH1POLBALDH1A1
	SCHEMBL3555649	0.76	PTGS2 (0.34)	PTGS2
	SCHEMBL4684915	0.76	ELANE (0.40)	LMNAGAAPOLBALDH1A1MEN1
	SCHEMBL752436	0.76	LMNA (0.38)	LMNAGAAPOLBALDH1A1HTT
	SCHEMBL7698140	0.75	LMNA (0.44)	LMNAGAAIDH1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.