SCHEMBL755692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4684915	0.84	ELANE (0.40)	LMNAGAAELANEHTR2BCREB1
	SCHEMBL7622844	0.83	KDM4E (0.48)	LMNAGAAHTR2BCREB1POLB
	SCHEMBL752436	0.82	LMNA (0.38)	LMNAGAAELANEHTR2BCREB1
	SCHEMBL16921605	0.82	LMNA (0.44)	LMNAGAAHTR2BCREB1POLB
	SCHEMBL16925513	0.82	DUT (0.32)	LMNAPOLBALDH1A1KDM4E
	SCHEMBL3560853	0.81	LMNA (0.43)	LMNAGAAELANECREB1POLB
	SCHEMBL10290053	0.80	CREB1 (0.41)	LMNAGAAHTR2BCREB1POLB
	SCHEMBL18837875	0.80	ALDH1A1 (0.43)	LMNAGAAHTR2BCREB1POLB
	SCHEMBL4318848	0.80	HTR2B (0.43)	LMNAGAAHTR2BCREB1POLB
	SCHEMBL10443608	0.79	MAOA (0.43)	LMNAGAAELANEHTR2BCREB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.