Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35615 | 0.91 | TSHR (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4883024 | 0.83 | TSHR (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL393526 | 0.83 | TSHR (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL5202793 | 0.82 | TSHR (0.39) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL65597 | 0.81 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5575873 | 0.81 | TSHR (0.38) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL65281 | 0.80 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL23673322 | 0.79 | TSHR (0.40) | THRBTSHR | |
| SCHEMBL397194 | 0.79 | TSHR (0.44) | THRBTSHRALDH1A1 | |
| SCHEMBL331867 | 0.79 | TSHR (0.38) | THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-2125833-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2125834-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |