SCHEMBL5068019

SCHEMBL5068019

C=C(C)C(=O)OCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C.C=C(C)C(=O)OCCC[Si](C)(C)OCC.C=C(C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5575873 0.82 TSHR (0.38) TSHRTHRB
SCHEMBL5068016 0.82 TSHR (0.41) TSHRTHRB
SCHEMBL35615 0.82 TSHR (0.46) TSHRTHRB
SCHEMBL5202793 0.79 TSHR (0.39) TSHRTHRB
SCHEMBL5702087 0.78 TSHR (0.49) TSHRTHRB
SCHEMBL64874 0.78 TSHR (0.54) TSHRTHRB
SCHEMBL35807 0.77 TSHR (0.51) TSHRTHRB
SCHEMBL2106287 0.76 TSHR (0.49) TSHRTHRB
SCHEMBL333002 0.76 TSHR (0.50) TSHRTHRB
SCHEMBL4883024 0.76 TSHR (0.42) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928979-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS Rolic AG (CH) 2008-06-11 EP disclosed
WO-2007033506-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2007-03-29 WO disclosed