Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydroferulic Acid Ethyl Ester SCHEMBL356300 | 0.90 | ALOX5 (0.67) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8890692 | 0.89 | ALOX5 (0.49) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8889417 | 0.89 | TUBB4A (0.58) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL4288930 | 0.86 | CYP1A2 (0.67) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL11733932 | 0.85 | LMNA (0.55) | CYP1A2CYP3A4LTA4HCYP2D6 | |
| SCHEMBL14503249 | 0.84 | ALOX5 (0.58) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL11936829 | 0.83 | CYP1A2 (0.71) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL7824983 | 0.83 | ALOX5 (0.71) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL906528 | 0.83 | ALOX5 (0.67) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL4007566 | 0.83 | ALOX5 (0.77) | ALOX5CYP1A2CYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925755-B1 | NEUROPROTECTIVE AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV WAYNE STATE (US) | 2021-09-08 | — | — | EP | disclosed |
| US-10874669-B2 | Neuroprotective agents for treatment of neurodegenerative diseases | WAYNE STATE UNIVERSITY (US) | 2020-12-29 | — | — | US | disclosed |
| US-20190076426-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | WAYNE STATE UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-20190038622-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | WAYNE STATE UNIVERSITY | 2019-02-07 | — | — | US | disclosed |
| US-10125127-B2 | Neuroprotective agents for treatment of neurodegenerative diseases | WAYNE STATE UNIVERSITY (US) | 2018-11-13 | — | — | US | disclosed |
| US-20150299180-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | WAYNE STATE UNIVERSITY (US) | 2015-10-22 | — | — | US | disclosed |
| EP-2925755-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | Wayne State University (US) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014085600-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | WAYNE STATE UNIVERSITY (US) | 2014-06-05 | — | — | WO | disclosed |
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299180-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | RTN4, NR4A1, NR4A3 | ALOX5 1093/4885CYP1A2 3571/4885CYP3A4 1849/4885 |
| US-20190076426-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | SMN1; SMN2, PARK7, SNCA | ALOX5 3375/4885CYP1A2 3835/4885CYP3A4 4526/4885 |
| US-20190038622-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | SMN1; SMN2, PARK7, SNCA | ALOX5 3375/4885CYP1A2 3835/4885CYP3A4 4526/4885 |
| US-10125127-B2 | Neuroprotective agents for treatment of neurodegenerative diseases | RTN4, NR4A1, NR4A3 | ALOX5 1093/4885CYP1A2 3571/4885CYP3A4 1849/4885 |
| US-10874669-B2 | Neuroprotective agents for treatment of neurodegenerative diseases | SMN1; SMN2, PARK7, SNCA | ALOX5 3375/4885CYP1A2 3835/4885CYP3A4 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.