SCHEMBL3570833

SCHEMBL3570833

Cc1cccc(C[S+]([O-])Cc2cccc(C)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.50
IDO1 P14902 2/20 0.48
ACHE P22303 1/20 0.46
HRH3 Q9Y5N1 1/20 0.42
MAOB P27338 2/20 0.41
CTBP2 P56545 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DAO P14920 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20198221 0.94 TAAR1 (0.46) TAAR1IDO1ACHEHRH3MAOB
SCHEMBL6589934 0.85 TAAR1 (0.48) TAAR1IDO1ACHEHRH3MAOB
SCHEMBL30837414 0.74 TAAR1 (0.50) TAAR1IDO1MAOBMEN1KMT2A
SCHEMBL30837419 0.74 TAAR1 (0.50) TAAR1IDO1MAOBCYP11B1CYP11B2
SCHEMBL3564528 0.74 PNMT (0.54) TAAR1IDO1
SCHEMBL3565658 0.74 TAAR1 (0.50) TAAR1IDO1MAOBCYP11B1CYP11B2
SCHEMBL776359 0.74 TAAR1 (0.50) TAAR1IDO1MAOBMEN1KMT2A
SCHEMBL30837416 0.74 PNMT (0.54) TAAR1IDO1
SCHEMBL20198224 0.74 LMNA (0.47) ACHEPOLBTDP1
SCHEMBL30000562 0.74 TAAR1 (0.60) TAAR1IDO1ACHEHRH3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485587-B Method for preparing sulfoxide compound by one-step reaction of benzyl chloride compound and thiophenol under metal-free condition 陕西师范大学 2020-10-16 CN disclosed
CN-109485587-A The method that benzyl chlorides chemical compound and thiophenol prepare sulfoxide compound in no metal condition next step reaction 陕西师范大学 2019-03-19 CN disclosed
EP-1675930-B1 NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2018-05-30 EP disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-7776582-B2 for gas chromatography; identifying an optically enhanced chiral ionic liquid (OCIL) for enantiomeric resolution SIGMA-ALDRICH CO. (US) 2010-08-17 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20090145197-A1 Optically Enhanced Chiral Ionic Liquids SIGMA-ALDRICH CO. NEWCO INC. 2009-06-11 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20060014955-A1 Optically enhanced chiral ionic liquids ADVANCED SEPARATION TECHNOLOGIES INC. (US) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014955-A1 Optically enhanced chiral ionic liquids GCG, INF2, ELOVL3 TAAR1 1789/4885IDO1 737/4885ACHE 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.