Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1430901 | 0.85 | TRPM8 (0.65) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL300007 | 0.83 | TAAR1 (0.62) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL7406 | 0.83 | CYP3A4 (0.62) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL5944204 | 0.83 | TRPM8 (0.59) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL29364835 | 0.83 | CYP3A4 (0.62) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL1461888 | 0.83 | CYP3A4 (0.68) | HDAC1HDAC2HDAC3HDAC6TAAR1 | |
| SCHEMBL17694670 | 0.81 | CTNNB1 (0.66) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL13545151 | 0.81 | TRPM8 (0.57) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL108087 | 0.80 | TAAR1 (0.77) | TAAR1CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6869142 | 0.80 | HDAC1 (0.60) | TRPM8HDAC1HDAC2HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116218289-B | Skin-feel artistic coating and preparation method thereof | 福建比美特环保集团有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-116218289-A | Skin-feel artistic coating and preparation method thereof | 福建比美特环保集团有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-112979625-A | Synthesis method and application of piperlongumine | 广西馨海药业科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-116218289-B | Skin-feel artistic coating and preparation method thereof | 福建比美特环保集团有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-116218289-A | Skin-feel artistic coating and preparation method thereof | 福建比美特环保集团有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-112979625-A | Synthesis method and application of piperlongumine | 广西馨海药业科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112979625-A | Synthesis method and application of piperlongumine | 广西馨海药业科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| CN-101123962-A | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS INC (US) | 2008-02-13 | — | — | CN | disclosed |
| EP-1817030-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | Kalypsys, Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060424-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | KALYPSYS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20060116515-A1 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. | 2006-06-01 | — | — | US | disclosed |
| EP-1042294-B1 | HETEROCYCLIC CYTOTOXIC AGENTS | UNIV RUTGERS (US) | 2004-08-11 | — | — | EP | disclosed |
| US-6486167-B1 | Heterocyclic cytotoxic agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-11-26 | — | — | US | disclosed |
| EP-1042294-A1 | HETEROCYCLIC CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031067-A1 | HETEROCYCLIC CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116515-A1 | Inducible nitric oxide synthase dimerization inhibitors | NOS3, NOS2, NOS1 | TRPM8 2244/4885HDAC1 2786/4885HDAC2 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.