Acrylic Acid

Acrylic Acid

SCHEMBL356557

C=CC(=O)O.CCOC(=O)C(C)Cl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.41
LMNA P02545 3/20 0.40
TSHR P16473 4/20 0.39
ALDH1A1 P00352 6/20 0.36
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 2/20 0.33
PIN1 Q13526 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL604352 0.85
SCHEMBL5603 0.85
SCHEMBL17617672 0.85
Acrylic Acid SCHEMBL7116437 0.82 HCAR2 (0.42) HCAR2LMNATSHRALDH1A1HSD17B10
Acetone SCHEMBL10801926 0.81 ALDH1A1 (0.48) LMNATSHRALDH1A1HSD17B10HPGD
Acrylic Acid Ethyl Ester SCHEMBL3655026 0.78 TSHR (0.52) HCAR2LMNATSHRALDH1A1HSD17B10
Acrylic Acid SCHEMBL28837980 0.78 LMNA (0.42) LMNATSHR
Acrylic Acid SCHEMBL28853307 0.77 LMNA (0.46) HCAR2LMNATSHRALDH1A1HSD17B10
Acrylic Acid SCHEMBL29212705 0.76 LMNA (0.50) HCAR2LMNATSHRALDH1A1HSD17B10
Acrylic Acid SCHEMBL28676784 0.75 LMNA (0.56) HCAR2LMNATSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361908-B2 Modified surface material, method for preparing same and uses thereof UNIVERSITE PARIS 7-DENIS DIDEROT (FR) 2013-01-29 US disclosed
US-20120015138-A1 MODIFIED SURFACE MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF ALCHIMEDICS (FR) 2012-01-19 US disclosed
US-8053567-B2 forming undercoatings on semiconductor by polymerizing monomers with diazonium salt which can electrochemical reduction having a polymerization initiator function; in situ free radical polymerization; stents, implants, prostheses; corrosion resistance Universite Paris 7—Denis Diderot (FR) 2011-11-08 US disclosed
US-20080064783-A1 Modified Surface Material, Method for Preparing Same and Uses Thereof ALCHIMEDICS (FR) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064783-A1 Modified Surface Material, Method for Preparing Same and Uses Thereof SOAT2, SOAT1, INMT HCAR2 4179/4885LMNA 1471/4885TSHR 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.