Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 3/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.46 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561309 | 0.89 | FABP4 (0.48) | FABP4FABP5ALPLSLC22A12IDH1 | |
| SCHEMBL3556453 | 0.87 | RXRA (0.53) | FABP4FABP5ALPLSLC22A12IDH1 | |
| SCHEMBL3554971 | 0.86 | MEN1 (0.51) | FABP4FABP5ALPLSLC22A12SLC16A3 | |
| SCHEMBL3554994 | 0.84 | SLC16A3 (0.50) | FABP4FABP5ALPLSLC22A12IDH1 | |
| SCHEMBL3550821 | 0.84 | MEN1 (0.60) | SLC22A12ALDH1A1MEN1KMT2AMCL1 | |
| SCHEMBL3560780 | 0.83 | HDAC1 (0.51) | IDH1AVPR2GPR27MEN1KMT2A | |
| SCHEMBL3551918 | 0.83 | MEN1 (0.50) | FABP4FABP5ALPLSLC22A12IDH1 | |
| SCHEMBL3559119 | 0.82 | PTK2B (0.50) | FABP4FABP5SLC16A3ALDH1A1MEN1 | |
| SCHEMBL3557128 | 0.82 | MEN1 (0.49) | FABP4FABP5ALPLSLC16A3ALDH1A1 | |
| SCHEMBL3560779 | 0.81 | SLC16A3 (0.64) | ALPLSLC16A3MEN1KMT2ASLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | FABP4 251/4885FABP5 799/4885ALPL 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.