Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 8/20 | 0.35 |
| ▸ | DUT | P33316 | 7/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577226 | 0.89 | DUT (0.31) | P2RY6DUT | |
| SCHEMBL6244002 | 0.85 | TK1 (0.36) | — | |
| SCHEMBL10645179 | 0.83 | TYMS (0.31) | — | |
| SCHEMBL10642960 | 0.83 | — | — | |
| SCHEMBL5960168 | 0.78 | P2RY14 (0.33) | P2RY6DUTP2RY14P2RY2P2RY4 | |
| SCHEMBL7511946 | 0.77 | — | — | |
| SCHEMBL8205228 | 0.76 | DUT (0.32) | P2RY6DUTP2RY14P2RY2P2RY4 | |
| SCHEMBL7201619 | 0.74 | P2RY14 (0.31) | P2RY14 | |
| SCHEMBL7922853 | 0.74 | TK2 (0.34) | — | |
| SCHEMBL8176133 | 0.73 | TK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075924-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-25 | — | — | US | disclosed |
| US-7601702-B2 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2009-10-13 | — | — | US | disclosed |
| US-20080300216-A1 | Dutpase Inhibitors | MEDIVIR AB (SE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300216-A1 | Dutpase Inhibitors | DUT, DHODH, POLR2H | P2RY6 2832/4885DUT 1/4885P2RY14 3517/4885 |
| US-20100075924-A1 | DUTPASE INHIBITORS | DUT, DHODH, CCNO | P2RY6 2755/4885DUT 1/4885P2RY14 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.