Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3567690 | 0.74 | P2RY6 (0.35) | P2RY14 | |
| SCHEMBL5960168 | 0.73 | P2RY14 (0.33) | P2RY14 | |
| SCHEMBL8205228 | 0.71 | DUT (0.32) | P2RY14 | |
| SCHEMBL3577226 | 0.71 | DUT (0.31) | — | |
| SCHEMBL3516066 | 0.70 | TK2 (0.32) | — | |
| SCHEMBL7901421 | 0.69 | TK1 (0.32) | — | |
| SCHEMBL2515798 | 0.68 | P2RY6 (0.34) | P2RY14CYP3A4CYP2C9 | |
| SCHEMBL3514646 | 0.67 | P2RY6 (0.33) | — | |
| SCHEMBL9218584 | 0.67 | P2RY2 (0.40) | P2RY14 | |
| Methylene Chloride SCHEMBL4340806 | 0.66 | P2RY2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602857-B1 | Antisense modulation of PTP1B expression | ISIS PHARMACEUTICALS, INC. | 2003-08-05 | — | — | US | disclosed |