Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 4/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ESRRB | O95718 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12520898 | 0.81 | TP53 (0.53) | TP53MAPTESRRGC5AR1BCL2 | |
| SCHEMBL3574025 | 0.79 | C5AR1 (0.46) | TP53MAPTESRRGC5AR1CA12 | |
| SCHEMBL3581435 | 0.78 | TP53 (0.41) | TP53MAPTF2F10F7 | |
| SCHEMBL749564 | 0.78 | TP53 (0.41) | TP53MAPTF2F10F7 | |
| SCHEMBL12521008 | 0.77 | TP53 (0.48) | TP53MAPTESRRGBCL2MCHR1 | |
| SCHEMBL3585062 | 0.77 | LMNA (0.40) | C5AR1LMNAGAALPAR1LPAR5 | |
| SCHEMBL12520957 | 0.77 | TP53 (0.43) | TP53MAPTF2F10F7 | |
| SCHEMBL747155 | 0.77 | TP53 (0.38) | TP53MAPTF2F10F7 | |
| Hydrochloric Acid SCHEMBL748268 | 0.76 | TP53 (0.38) | TP53MAPTF2F10F7 | |
| SCHEMBL12521175 | 0.75 | LPAR1 (0.41) | TP53MAPTESRRGC5AR1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |