Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295130 | 0.94 | — | — | |
| SCHEMBL1862536 | 0.94 | MEN1 (0.30) | — | |
| SCHEMBL15555175 | 0.94 | — | — | |
| SCHEMBL15555718 | 0.94 | — | — | |
| Lithium Ion SCHEMBL1865839 | 0.94 | — | — | |
| Lithium Ion SCHEMBL31748056 | 0.92 | — | — | |
| Tetrylammonium SCHEMBL16107498 | 0.79 | TSHR (0.33) | — | |
| Potassium Ion SCHEMBL357233 | 0.78 | — | — | |
| Potassium Ion SCHEMBL5323555 | 0.78 | — | — | |
| SCHEMBL358110 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376379-B2 | Process for the synthesis of tetrafluoroethanesulfonic acid | SRF LIMITED (IN) | 2016-06-28 | — | — | US | claimed |
| US-20150259281-A1 | PROCESS FOR THE SYNTHESIS OF TETRAFLUOROETHANESULFONIC ACID | SRF LIMITED (IN) | 2015-09-17 | — | — | US | claimed |
| WO-2014020614-A2 | PROCESS FOR THE SYNTHESIS OF TETRAFLUOROETHANESULFONIC ACID | SRF LIMITED (IN) | 2014-02-06 | — | — | WO | claimed |
| US-7947770-B2 | blend of polycarbonate resin prepared from diphenylcarbonate and 2,2-bis(4-hydroxyphenyl)propane; polytetrafluoroethylene antidrip agent; tetrafluoroalkylsulfonate or hexafluorodialkylsulfonimide salt of Na, K, Cs, Li or a pyridium, pydridazinium, phosphonium, ammonium etc.; protective devices | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-24 | — | — | US | claimed |
| US-20080221241-A1 | Flame Retardant Polycarbonate Compositions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-11 | — | — | US | claimed |
| US-9376379-B2 | Process for the synthesis of tetrafluoroethanesulfonic acid | SRF LIMITED (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20150259281-A1 | PROCESS FOR THE SYNTHESIS OF TETRAFLUOROETHANESULFONIC ACID | SRF LIMITED (IN) | 2015-09-17 | — | — | US | disclosed |
| EP-2118194-B1 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS | DU PONT (US) | 2014-12-03 | — | — | EP | disclosed |
| US-20140286849-A1 | Mixtures of Ammonia and Ionic Liquids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-25 | — | — | US | disclosed |
| US-8715521-B2 | Absorption cycle utilizing ionic liquid as working fluid | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-06 | — | — | US | disclosed |
| US-8707720-B2 | Hybrid vapor compression-absorption cycle | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| WO-2014020614-A2 | PROCESS FOR THE SYNTHESIS OF TETRAFLUOROETHANESULFONIC ACID | SRF LIMITED (IN) | 2014-02-06 | — | — | WO | disclosed |
| US-20070066854-A1 | Preparation of polytrimethylene ether glycol and copolymers thereof | THE CHEMOURS COMPANY FC, LLC | 2007-03-22 | — | — | US | disclosed |
| US-20070066852-A1 | Preparation of poly(tetramethylene) glycol | THE CHEMOURS COMPANY FC, LLC | 2007-03-22 | — | — | US | disclosed |
| US-20070019708-A1 | Hybrid vapor compression-absorption cycle | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-01-25 | — | — | US | disclosed |
| WO-2006133331-A1 | MANUFACTURE OF HYDROFLUOROALKANESULFONIC ACIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-14 | — | — | WO | disclosed |
| US-20060276671-A1 | Manufacture of hydrofluoroalkanesulfonic acids | THE CHEMOURS COMPANY FC, LLC | 2006-12-07 | — | — | US | disclosed |
| WO-2006124776-A2 | HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060197053-A1 | Absorption cycle utilizing ionic liquid as working fluid | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-09-07 | — | — | US | disclosed |
| WO-2006084262-A1 | ABSORPTION CYCLE UTILIZING IONIC LIQUID AS WORKING FLUID | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |