Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3569921 | 0.92 | SERPINE1 (0.47) | SERPINE1KDM4EHSD17B10PPARGNR1H4 | |
| SCHEMBL3578904 | 0.92 | LMNA (0.44) | SERPINE1SLC2A1KDM4EHSD17B10PPARG | |
| SCHEMBL3581404 | 0.89 | CNR1 (0.43) | SERPINE1KDM4EHSD17B10PPARGNR1H4 | |
| SCHEMBL3569048 | 0.87 | SERPINE1 (0.42) | SERPINE1KDM4EHSD17B10PPARGNR1H4 | |
| SCHEMBL3569791 | 0.87 | LPAR1 (0.43) | SERPINE1KDM4EHSD17B10NR1H4LPAR1 | |
| SCHEMBL3577993 | 0.85 | HSP90AA1 (0.47) | SERPINE1KDM4EHSD17B10PPARGNR1H4 | |
| SCHEMBL3584423 | 0.84 | LPAR1 (0.43) | SLC2A1KDM4ENR1H4LPAR1LPAR5 | |
| SCHEMBL3580426 | 0.83 | HSPH1 (0.42) | SERPINE1SLC2A1PPARGNR1H4LPAR1 | |
| SCHEMBL3575609 | 0.83 | LMNA (0.43) | SERPINE1SLC2A1LPAR1LPAR5C5AR1 | |
| SCHEMBL3584396 | 0.82 | C5AR1 (0.44) | SERPINE1KDM4ELPAR1LPAR5C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |