Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625493 | 0.93 | VCAM1 (0.61) | ALDH1A1MAPTTDP1SRD5A2LMNA | |
| SCHEMBL10948000 | 0.92 | VCAM1 (0.62) | ALDH1A1MAPTTDP1LMNAGAA | |
| SCHEMBL11466888 | 0.87 | VCAM1 (0.68) | ALDH1A1MAPTTDP1LMNAVCAM1 | |
| SCHEMBL3572303 | 0.86 | CES2 (0.57) | ALDH1A1TDP1VCAM1MAPK1POLB | |
| SCHEMBL10954224 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTTDP1LMNAGAA | |
| SCHEMBL8622602 | 0.85 | VCAM1 (0.56) | ALDH1A1MAPTTDP1LMNAGAA | |
| Methyl Alcohol SCHEMBL27754511 | 0.84 | VCAM1 (0.64) | ALDH1A1MAPTLMNAGAAVCAM1 | |
| Carbamic Acid SCHEMBL28096989 | 0.83 | MAPK1 (0.62) | ALDH1A1MAPTTDP1LMNAVCAM1 | |
| SCHEMBL10953459 | 0.83 | VCAM1 (0.81) | ALDH1A1MAPTLMNAGAAVCAM1 | |
| SCHEMBL10955626 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455529-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455529-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110319460-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2011-12-29 | — | — | US | disclosed |
| US-20110319460-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2011-12-29 | — | — | US | disclosed |
| US-8034957-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-8034957-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-7749530-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-7749530-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-7749530-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20100168199-A1 | Kinase Inhibitors | ALLENGAN, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| US-5710334-A | PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0572196-B1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5480965-A | BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0572196-A1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-4556738-A | CATALYTICALLY REDUCING AND DEHALOGENATING A DINITROBENZOPHENONE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168199-A1 | Kinase Inhibitors | ABL1, LCK, ERBB2 | ALDH1A1 2379/4885MAPT 2433/4885TDP1 1059/4885 |
| US-20110319460-A1 | KINASE INHIBITORS | ABL1, LCK, ERBB2 | ALDH1A1 2379/4885MAPT 2433/4885TDP1 1059/4885 |
| US-20070032478-A1 | Kinase Inhibitors | ABL1, LCK, ERBB2 | ALDH1A1 2379/4885MAPT 2433/4885TDP1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.