Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948000 | 0.93 | VCAM1 (0.62) | VCAM1MAPK1MAPTGAAALDH1A1 | |
| SCHEMBL11466888 | 0.92 | VCAM1 (0.68) | VCAM1MAPK1MAPTALDH1A1CYP2D6 | |
| SCHEMBL8625493 | 0.91 | VCAM1 (0.61) | VCAM1MAPK1MAPTGAAALDH1A1 | |
| SCHEMBL3572303 | 0.91 | CES2 (0.57) | VCAM1MAPK1ALDH1A1TDP1CES2 | |
| Methyl Alcohol SCHEMBL27754511 | 0.89 | VCAM1 (0.64) | VCAM1MAPK1MAPTGAAALDH1A1 | |
| Carbamic Acid SCHEMBL28096989 | 0.88 | MAPK1 (0.62) | VCAM1MAPK1MAPTALDH1A1CYP2D6 | |
| SCHEMBL3575705 | 0.85 | ALDH1A1 (0.58) | VCAM1MAPK1MAPTGAAALDH1A1 | |
| SCHEMBL10953459 | 0.84 | VCAM1 (0.81) | VCAM1MAPK1MAPTGAAALDH1A1 | |
| SCHEMBL2156916 | 0.82 | CES1 (0.54) | VCAM1MAPTGAAALDH1A1CYP2D6 | |
| SCHEMBL99875 | 0.81 | CASP6 (0.70) | LMNACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710334-A | PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0572196-B1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0474501-B1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5480965-A | BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5322962-A | Produce polyimides with high heat and chemical resistance, processability | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0572196-A1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-5231160-A | AROMATIC DIAMINE COMPOUND, PREPARATION PROCESS OF SAME AND POLYIMIDE PREPARED FROM SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0474501-A1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |