SCHEMBL357605

SCHEMBL357605

C[Si](C)(Oc1ccc(N)cc1)Oc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.52
MAPK1 P28482 2/20 0.52
ALDH1A1 P00352 8/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TEAD4 Q15561 1/20 0.46
MAPT P10636 6/20 0.44
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
HPGD P15428 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TP53 P04637 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MAOA P21397 2/20 0.42
MEN1 O00255 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358721 0.93 ALDH1A1 (0.50) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL3309381 0.90 TDP1 (0.48) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL8722725 0.88 TDP1 (0.46) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL2335338 0.84 TDP1 (0.52) TDP1MAPK1ALDH1A1CYP3A4TSHR
Aniline SCHEMBL28423123 0.83 TSHR (0.50) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL28446950 0.83 TDP1 (0.41) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL15375276 0.82 TDP1 (0.56) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL5072155 0.81 RAB9A (0.49) TDP1ALDH1A1CYP3A4TSHRMAPT
SCHEMBL20653104 0.78 ALDH1A1 (0.55) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL1166684 0.77 PREP (0.46) TDP1MAPK1ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613717-B Thermosetting polyimide resin with high heat resistance and preparation method thereof SICHUAN UNIVERSITY (CN) 2026-05-26 CN claimed
CN-120118677-A Gel breaker for shale oil and preparation process thereof 广饶六合化工有限公司 2025-06-10 CN claimed
CN-119286060-B Preparation method and application of modified rutile type nano titanium dioxide 广东惠云钛业股份有限公司 2025-05-30 CN claimed
CN-119955095-A Photosensitive polyimide material with low glass transition temperature and preparation method and application thereof 深圳市化讯半导体材料有限公司 2025-05-09 CN claimed
CN-119119904-B High-temperature-resistant low-viscosity residual-glue-free protective film and preparation method thereof 江苏斯瑞达材料技术股份有限公司 2025-04-04 CN claimed
CN-119662027-A Preparation method and application of skidproof flexible silica gel with skin-friendly matte surface 东莞市莎利特新材料科技有限公司 2025-03-21 CN claimed
CN-119613717-A Thermosetting polyimide resin with high heat resistance and preparation method thereof 四川大学 2025-03-14 CN claimed
WO-2025030690-A1 SOLUBLE POLYIMIDE CASTING SOLUTION, THERMOPLASTIC POLYIMIDE FILM SINTERING LINE AND PREPARATION METHOD THEREFOR AND USE THEREOF 合肥汉之和新材料科技有限公司 2025-02-13 WO claimed
CN-119286060-A Preparation method and application of modified rutile type nano titanium dioxide 广东惠云钛业股份有限公司 2025-01-10 CN claimed
CN-116042159-B Aldehyde-free impregnating adhesive and preparation method thereof 万华化学集团股份有限公司 2025-01-10 CN claimed
US-8372257-B2 Electrodeposition coating material and electrodeposition method MITSUBISHI CABLE INDUSTRIES, LTD. (JP) 2013-02-12 US claimed
US-8257901-B2 Polyimide-based polymers, copolymers thereof and positive type photoresist compositions comprising the same LG CHEM, LTD. (KR) 2012-09-04 US claimed
US-20100108533-A1 ELECTRODEPOSITION COATING MATERIAL AND ELECTRODEPOSITION METHOD MITSUBISHI MATERIALS CORPORATION (JP) 2010-05-06 US claimed
US-20090200166-A1 Method of Analyzing Hemoglobin by Capillary Eletrophoresis ARKRAY, INC. (JP) 2009-08-13 US claimed
US-20070135601-A1 Initiator systems for polymerisable compositions HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (US) 2007-06-14 US claimed
JP-2007510788-A 2007-04-26 JP claimed
EP-1685165-A1 INITIATOR SYSTEMS FOR POLYMERISABLE COMPOSITIONS Huntsman Advanced Materials (Switzerland) GmbH (CH) 2006-08-02 EP claimed
WO-2005044867-A1 INITIATOR SYSTEMS FOR POLYMERISABLE COMPOSITIONS HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-05-19 WO claimed
US-5248760-A CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES UNC AT CHARLOTTE (US) 1993-09-28 US claimed
WO-1992013024-A1 CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) 1992-08-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135601-A1 Initiator systems for polymerisable compositions PFAS, PTK2, PNN TDP1 2297/4885MAPK1 3403/4885ALDH1A1 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.