SCHEMBL357875

SCHEMBL357875

CCC(C)c1ccccc1CO

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
GABRA1 P14867 3/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRB2 P47870 2/20 0.40
TRPA1 O75762 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
RORC P51449 1/20 0.38
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
HTT P42858 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6428005 0.88 TSHR (0.49) TSHRHSP90AA1HSP90AB1GABRA1GABRG2
SCHEMBL3627333 0.83 TSHR (0.59) TSHRGABRA1GABRB2RORCHTT
SCHEMBL9838740 0.83 TSHR (0.59) TSHRGABRA1GABRB2RORCHTT
SCHEMBL23219814 0.81 TSHR (0.48) TSHRHSP90AA1HSP90AB1GABRA1GABRG2
SCHEMBL12981697 0.81 TSHR (0.42) TSHRGABRA1GABRG2GABRB3GABRB2
SCHEMBL5353085 0.81 TSHR (0.57) TSHRHSP90AA1HSP90AB1GABRA1GABRB2
SCHEMBL357956 0.80 GABRA1 (0.58) TSHRHSP90AA1HSP90AB1GABRA1GABRG2
Hydrogen Peroxide SCHEMBL3675725 0.80 TSHR (0.74) TSHRGABRA1GABRB2TRPA1RORC
SCHEMBL994607 0.79 TSHR (0.73) TSHRGABRA1GABRG2GABRB3GABRB2
SCHEMBL394969 0.79 TSHR (0.55) TSHRHSP90AA1HSP90AB1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9607849-B2 Pattern-forming method and resist underlayer film-forming composition JSR CORPORATION (JP) 2017-03-28 US disclosed
US-9170493-B2 Resist underlayer film-forming composition, pattern-forming method and resist underlayer film JSR CORPORATION (JP) 2015-10-27 US disclosed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP disclosed
US-20140220783-A1 PATTERN-FORMING METHOD AND RESIST UNDERLAYER FILM-FORMING COMPOSITION JSR CORPORATION (JP) 2014-08-07 US disclosed
EP-1547995-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
EP-2418197-B1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
US-8663794-B2 Control of birefringence dispersion utilizing nanocomposites NITTO DENKO CORPORATION (JP) 2014-03-04 US disclosed
US-8461370-B2 Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US disclosed
EP-2537828-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT Sumitomo Chemical Company, Limited (JP) 2012-12-26 EP disclosed
US-20120310003-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-06 US disclosed
EP-0992479-B1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL CO (JP) 2003-01-02 EP disclosed
US-20020151741-A1 Process for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-17 US disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
US-6441220-B1 ESTERIFICATION WITH ALCOHOL IN PRESENCE OF BASIC CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-27 US disclosed
EP-1227077-A2 Process for producing cyclopropanecarboxylates Sumitomo Chemical Co.,Ltd. (JP) 2002-07-31 EP disclosed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed
EP-1061065-A2 Methods for producing cyclopropane carboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-20 EP disclosed
EP-0992479-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-12 EP disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151741-A1 Process for producing cyclopropanecarboxylates CYC1, CYP21A2, CYP2A6 TSHR 4329/4885HSP90AA1 1533/4885HSP90AB1 1889/4885
US-20120310003-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT MCCC2, AOC2, DDC TSHR 1331/4885HSP90AA1 3645/4885HSP90AB1 4391/4885
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 TSHR 1601/4885HSP90AA1 4287/4885HSP90AB1 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.