SCHEMBL4534936

SCHEMBL4534936

Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCCCCCCCCCCSC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 14/20 0.45
CYP24A1 Q07973 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057736 1.00 KIF11 (0.45) KIF11CYP24A1CA12CA1CA9
SCHEMBL4512510 0.92 KIF11 (0.48) KIF11CYP24A1CA12CA1CA9
SCHEMBL4526888 0.92 KIF11 (0.48) KIF11CYP24A1CA12CA1CA9
SCHEMBL357884 0.84 KIF11 (0.45) KIF11ALDH1A1
SCHEMBL4303777 0.82 TK1 (0.43) KIF11CYP24A1CA12CA1CA9
SCHEMBL4013278 0.80 TK2 (0.42) KIF11CYP24A1CA12CA1CA9
SCHEMBL20120297 0.79 ALDH1A1 (0.47) CYP24A1CA12CA1CA9CYP3A4
SCHEMBL12390525 0.79 KIF11 (0.47) KIF11
SCHEMBL9999946 0.79 KIF11 (0.47) KIF11
Biphenyl SCHEMBL17044634 0.79 CYP24A1 (0.44) CYP24A1CA12CA1CA9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325262-A1 Immobilization of biological molecules onto surfaces coated with monolayers SURFACE LOGIX, INC. 2009-12-31 US disclosed
US-7439056-B2 Peelable and resealable devices for arraying materials SURFACE LOGIX INC. (US) 2008-10-21 US disclosed
US-7371563-B2 Peelable and resealable devices for biochemical assays SURFACE LOGIX, INC. (US) 2008-05-13 US disclosed
US-7001740-B2 Methods of arraying biological materials using peelable and resealable devices SURFACE LOGIX, INC. (US) 2006-02-21 US disclosed
US-20050250097-A1 METHODS OF ARRAYING BIOLOGICAL MATERIALS USING PEELABLE AND RESEALABLE DEVICES SURFACE LOGIX, LLC 2005-11-10 US disclosed
US-20050100974-A1 METHODS OF DETECTING IMMOBILIZED BIOMOLECULES SURFACE LOGIX, LLC 2005-05-12 US disclosed
US-6803205-B2 MONITORING ENZYME ACTIVITY IN SAMPLE; OBTAIN ENZYME SAMPLE, INSERT INTO RESEALABLE APPARATUS, EXPOSE TO SUBSTRATE, MEASURE ENZYME ACTIVITY SURFACE LOGIX, INC. 2004-10-12 US disclosed
US-20030073228-A1 Peelable and resealable devices for arraying materials SURFACE LOGIX, LLC 2003-04-17 US disclosed
US-20030032076-A1 Methods of measuring enzyme activity using peelable and resealable devices SURFACE LOGIX, LLC 2003-02-13 US disclosed
US-20030032046-A1 Peelable and resealable devices for biochemical assays SURFACE LOGIX, LLC 2003-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325262-A1 Immobilization of biological molecules onto surfaces coated with monolayers EPCAM, ICAM1, MB KIF11 3822/4885CYP24A1 3520/4885CA12 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.