Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2840961 | 0.84 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3HRH3KMT2A | |
| SCHEMBL2839552 | 0.83 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3HRH3MEN1 | |
| SCHEMBL10954592 | 0.80 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3HRH3MEN1 | |
| SCHEMBL2841093 | 0.80 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3HRH3DRD2 | |
| SCHEMBL2841122 | 0.78 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL2843973 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3HRH3MEN1 | |
| Hydrochloric Acid SCHEMBL2844211 | 0.74 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| Maleic Acid SCHEMBL10956066 | 0.72 | LMNA (0.41) | SLC6A4SLC6A2SLC6A3HRH3MEN1 | |
| Fumaric Acid SCHEMBL10956074 | 0.72 | LMNA (0.41) | SLC6A4SLC6A2SLC6A3HRH3MEN1 | |
| Hydrochloric Acid SCHEMBL3575325 | 0.72 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | NIPPON SHINYAKU CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048537-A1 | HETEROARYL DERIVATIVES | OPRD1, OPRM1, OPRK1 | SLC6A4 185/4885SLC6A2 196/4885SLC6A3 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.