Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388001 | 0.80 | PLA2G10 (0.43) | PLA2G10PLA2G5SCN9ASCN10AKMT2A | |
| SCHEMBL6282329 | 0.79 | PLA2G10 (0.47) | PLA2G10PLA2G5SCN9ASCN10AKMT2A | |
| SCHEMBL16424936 | 0.78 | TSHR (0.49) | KMT2ARAB9AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17863606 | 0.77 | ALDH1A1 (0.39) | KMT2ARAB9AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28507628 | 0.76 | SMN1; SMN2 (0.45) | PLA2G10PLA2G5KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL26099054 | 0.76 | RET (0.40) | KMT2ARAB9AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL3584051 | 0.75 | PLA2G10 (0.42) | PLA2G10PLA2G5SCN9ASCN10ARAB9A | |
| SCHEMBL7278907 | 0.75 | PLA2G10 (0.45) | PLA2G10PLA2G5SCN9ASCN10AALDH1A1 | |
| SCHEMBL6877063 | 0.74 | KMT2A (0.42) | KMT2ARAB9AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL26452488 | 0.74 | KMT2A (0.53) | KMT2ARAB9AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
| US-20080132500-A1 | Antibiotic compounds | MERCK SHARP & DOHME CORP. | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | RPL5, RPL35, HAVCR2 | PLA2G10 3783/4885PLA2G5 3771/4885SCN9A 4396/4885 |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | PLA2G10 2197/4885PLA2G5 2031/4885SCN9A 1304/4885 |
| US-20080132500-A1 | Antibiotic compounds | NRDC, MRPL21, PEPD | PLA2G10 4539/4885PLA2G5 4793/4885SCN9A 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.