SCHEMBL35800

SCHEMBL35800

O=C(Br)c1ccc(CBr)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
ALDH1A1 P00352 2/20 0.43
TRPA1 O75762 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.41
HDAC6 Q9UBN7 2/20 0.40
PLK1 P53350 2/20 0.40
HDAC3 O15379 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
GSK3B P49841 4/20 0.39
PTPN1 P18031 3/20 0.39
HDAC8 Q9BY41 1/20 0.38
OGG1 O15527 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HDAC1 Q13547 1/20 0.38
POLB P06746 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187134 0.84 CES2 (0.61) CES2CES1ALDH1A1TRPA1TSHR
SCHEMBL9541276 0.84 CES2 (0.61) CES2CES1ALDH1A1TRPA1TSHR
SCHEMBL13679683 0.84 CES2 (0.83) CES2CES1ALDH1A1TRPA1TSHR
SCHEMBL688186 0.83 TP53 (0.47) CES2CES1ALDH1A1TSHRKMT2A
SCHEMBL220750 0.82 CES2 (0.65) CES2CES1ALDH1A1TRPA1TSHR
SCHEMBL31657756 0.81 OGG1 (0.63) CES2CES1ALDH1A1KMT2AHDAC6
SCHEMBL1290706 0.81 KMT2A (0.61) CES2CES1ALDH1A1TSHRKMT2A
SCHEMBL11612824 0.80 TDP1 (0.48) CES2CES1ALDH1A1KMT2APLK1
SCHEMBL526411 0.80 CES2 (0.57) CES2CES1ALDH1A1TRPA1TSHR
Hydrochloric Acid SCHEMBL1598137 0.80 CES2 (0.63) CES2CES1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798229-A Preparation method of imatinib dimer 中国食品药品检定研究院 2025-04-11 CN claimed
CN-115399179-A Application of polysaccharide-based cationic polymer in prevention and treatment of soil-borne diseases of agriculture and forestry 中国科学院化学研究所 2022-11-29 CN claimed
CN-108786500-A A kind of one-step method realizes the polyamide reverse osmose membrane and preparation method thereof in the active initiation site in surface 国家海洋局天津海水淡化与综合利用研究所 2018-11-13 CN claimed
EP-2566911-B1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-10-24 EP claimed
US-10073192-B2 Polymers and nanogel materials and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-09-11 US claimed
EP-2855544-B1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-06-20 EP claimed
CN-107936204-A Polymer and nano-gel material and its preparation and application 庄臣及庄臣视力保护公司 2018-04-20 CN claimed
US-9815979-B2 Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2017-11-14 US claimed
US-20170051145-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2017-02-23 US claimed
EP-2855547-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care Inc. (US) 2015-04-08 EP claimed
EP-2855544-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care Inc. (US) 2015-04-08 EP claimed
WO-2013176886-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 WO claimed
WO-2013177523-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 WO claimed
US-20130317131-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 US claimed
EP-2566911-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME Johnson & Johnson Vision Care, Inc. (US) 2013-03-13 EP claimed
WO-2011140318-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-11-10 WO claimed
US-20110275734-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. 2011-11-10 US claimed
CN-119798229-A Preparation method of imatinib dimer 中国食品药品检定研究院 2025-04-11 CN disclosed
EP-0305667-A2 Improved process for producing 5,10-dideaza-(5,6,7,8)-tetrahydrofolic acid AMERICAN CYANAMID COMPANY (US) 1989-03-08 EP disclosed
US-3959351-A INSECTICIDE, CHOLINESTERASE INHIBITOR RESEARCH CORPORATION (US) 1976-05-25 US disclosed