SCHEMBL187134

SCHEMBL187134

O=C(c1ccc(CBr)cc1)c1ccc(CBr)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
SRD5A2 P31213 9/20 0.48
LMNA P02545 3/20 0.48
MAPT P10636 3/20 0.48
HTT P42858 2/20 0.48
HPGD P15428 2/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
PKM P14618 1/20 0.48
ALDH1A1 P00352 4/20 0.46
TRPA1 O75762 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 1/20 0.41
BDKRB2 P30411 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541276 1.00 CES2 (0.61) CES2CES1SRD5A2LMNAMAPT
SCHEMBL118227 0.91 CES2 (0.77) CES2CES1SRD5A2LMNAMAPT
SCHEMBL7995493 0.91 LMNA (0.55) CES2CES1SRD5A2LMNAMAPT
SCHEMBL10654851 0.91 SRD5A2 (0.65) CES2CES1SRD5A2ALDH1A1TSHR
SCHEMBL2976204 0.89 PTPN1 (0.55) CES2CES1LMNAMAPTHPGD
SCHEMBL1744667 0.89 SRD5A2 (0.57) CES2CES1SRD5A2LMNAMAPT
SCHEMBL7013140 0.89 ALDH1A1 (0.67) CES2CES1SRD5A2LMNAHTT
SCHEMBL8546874 0.87 CES2 (0.60) CES2CES1SRD5A2ALDH1A1KMT2A
SCHEMBL9151945 0.85 CES2 (0.69) CES2CES1SRD5A2LMNAMAPT
SCHEMBL9541280 0.84 CES2 (0.62) CES2CES1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714992-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND Cemedine Co., Ltd. (JP) 2026-03-25 EP disclosed
WO-2024242005-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND セメダイン株式会社 2024-11-28 WO disclosed
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF THE SCRIPPS RESEARCH INSTITUTE 2024-06-27 US disclosed
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF THE SCRIPPS RESEARCH INSTITUTE 2024-06-27 US disclosed
US-20240191003-A1 COMPOSITION AND PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
CN-117908327-A Composition and photosensitive composition 东京应化工业株式会社 2024-04-19 CN disclosed
EP-4212180-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF The Scripps Research Institute (US) 2023-07-19 EP disclosed
US-11701345-B2 Car activator agents for cyclophosphamide-based treatments of cancer UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-07-18 US disclosed
US-20230210800-A1 HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS INC (US) 2023-07-06 US disclosed
US-20230119640-A1 ANTIBACTERIAL HYDROPHILIC COMPOUND SHENZHEN UNIVERSITY (CN) 2023-04-20 US disclosed
EP-0435687-A2 Process for isomerization of oxime ethers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed
EP-0119219-B1 COATING COMPOSITIONS AND THEIR USE IN THE RESTORATIVE AND/OR PROTECTIVE TREATMENT OF PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-23 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0002805-B1 PHOTOPOLYMERIZABLE COATING AND REGISTRATION MATERIALS,SUCH AS TRANSFER FOILS WITH A PHOTOSENSIBLE COATING AND PHOTORESIST MATERIALS, CONTAINING A PHOTOINITIATOR AND AN ORGANIC HALOGEN COMPOUND BASF Aktiengesellschaft (DE) 1981-01-07 EP disclosed
US-4239609-A PHOTORESISTS, RELIEF IMAGES BASF AKTIENGESELLSCHAFT (DE) 1980-12-16 US disclosed
EP-0002805-A1 Photopolymerizable coating and registration materials,such as transfer foils with a photosensible coating and photoresist materials, containing a photoinitiator and an organic halogen compound BASF Aktiengesellschaft (DE) 1979-07-11 EP disclosed
US-4107012-A COATINGS, PRINTING INKS BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4080382-A Haloalkyl benzophenone compounds suitable for use as initiators for photopolymerization EASTMAN KODAK COMPANY (US) 1978-03-21 US disclosed
US-4043887-A Benzophenone initiators for the photopolymerization of unsaturated compounds EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701345-B2 Car activator agents for cyclophosphamide-based treatments of cancer CYP2A6, CYP2B6, CYP4A11 CES2 95/4885CES1 94/4885SRD5A2 388/4885
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF SGMS1, SGMS2, PHOSPHO1 CES2 4147/4885CES1 2096/4885SRD5A2 4775/4885
US-20230210800-A1 HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES CYP27A1, NR1H3, PNLIP CES2 2238/4885CES1 250/4885SRD5A2 130/4885
US-20230119640-A1 ANTIBACTERIAL HYDROPHILIC COMPOUND HIRA, NOD2, CHLSN CES2 887/4885CES1 3525/4885SRD5A2 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.