Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520915 | 1.00 | ARG1 (0.34) | ARG1CYP1A2TSHRGRM2GRM3 | |
| SCHEMBL4264841 | 1.00 | ARG1 (0.34) | ARG1CYP1A2TSHRGRM2GRM3 | |
| SCHEMBL4381001 | 0.79 | CYP1A2 (0.46) | ARG1CYP1A2TSHRGRM2GRM3 | |
| SCHEMBL19522736 | 0.74 | CYP1A2 (0.32) | ARG1CYP1A2TSHRGRM2GRM3 | |
| SCHEMBL23484419 | 0.74 | CYP1A2 (0.32) | ARG1CYP1A2TSHRGRM2GRM3 | |
| SCHEMBL243671 | 0.73 | — | — | |
| SCHEMBL1033587 | 0.73 | — | — | |
| SCHEMBL11819887 | 0.73 | GRM4 (0.33) | CYP1A2TSHRGRM2GRM3GRM4 | |
| SCHEMBL709809 | 0.72 | FFAR3 (0.46) | CYP1A2TSHRGRM2GRM3GRM4 | |
| SCHEMBL11076963 | 0.72 | FFAR3 (0.46) | CYP1A2TSHRGRM2GRM3GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645768-B2 | Production of polyketides and other natural products | WYETH (US) | 2010-01-12 | — | — | US | disclosed |
| US-20080039486-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | GREGORY MATTHEW A | 2008-02-14 | — | — | US | disclosed |
| US-20080021211-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021211-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | FKBP14, FKBP4, FKBP2 | ARG1 4780/4885CYP1A2 3332/4885TSHR 3950/4885 |
| US-20080039486-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | FKBP14, FKBP4, FKBP2 | ARG1 4780/4885CYP1A2 3332/4885TSHR 3950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.