Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 0.74 |
| ▸ | GAA | P10253 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | SNCA | P37840 | 2/20 | 0.74 |
| ▸ | CYBB | P04839 | 2/20 | 0.74 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.74 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.74 |
| ▸ | APP | P05067 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30354356 | 0.89 | KCNH2 (0.63) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL22960542 | 0.89 | KCNH2 (0.63) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL31491519 | 0.87 | NOX1 (0.74) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL3586011 | 0.87 | NOX1 (0.74) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL3582632 | 0.85 | NOX1 (0.63) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL29375737 | 0.85 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL28073776 | 0.85 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL342449 | 0.85 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL24220378 | 0.84 | NOX1 (0.70) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL7978596 | 0.84 | NOX1 (0.74) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993555-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS (FR) | 2008-11-26 | — | — | EP | claimed |
| WO-2007101937-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-09-13 | — | — | WO | claimed |
| CN-119638644-A | Phenothiazine sulfonamide compound or salt thereof, and preparation method and application thereof | 郑州大学 | 2025-03-18 | — | — | CN | disclosed |
| US-8642591-B2 | Composition containing amidine derivatives or carboxamide derivatives and steroids, as a medicament | IPSEN PHARMA S.A.S. (FR) | 2014-02-04 | — | — | US | disclosed |
| EP-1993555-B1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | IPSEN PHARMA (FR) | 2012-10-17 | — | — | EP | disclosed |
| EP-1954288-B1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | IPSEN PHARMA (FR) | 2012-08-01 | — | — | EP | disclosed |
| CN-101291676-B | Amidine derivatives and their use as medicaments | SOD CONSEILS RECH APPLIC | 2011-09-14 | — | — | CN | disclosed |
| US-7862807-B2 | Dendrimers as molecular translocators | UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2011-01-04 | — | — | US | disclosed |
| US-7659266-B2 | Amidine derivatives and their applications as a medicament | S.C.R.A.S. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-20090311249-A1 | Capecitabine Combination Therapy | ARIAD PHARMACEUTICALS, INC. | 2009-12-17 | — | — | US | disclosed |
| US-20090149430-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2009-06-11 | — | — | US | disclosed |
| EP-0866695-A4 | COMBINATIONAL THERAPEUTIC METHODS EMPLOYING NITRIC OXIDE SCAVENGERS | MEDINOX INC (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-0938309-A4 | METHODS FOR IN VIVO REDUCTION OF IRON LEVELS AND COMPOSITIONS USEFUL THEREFOR | MEDINOX INC (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6093743-A | FOR IN VIVO REDUCTION OF LEVELS OF NITRIC OXIDE, SUCH AS ARE INDUCED BY A VARIETY OF DISEASE STATES, AND FOR TREATMENT OF INFECTIOUS AND/OR INFLAMMATORY CONDITIONS | MEDINOX INC. (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0938309-A1 | METHODS FOR IN VIVO REDUCTION OF IRON LEVELS AND COMPOSITIONS USEFUL THEREFOR | Medinox, Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5916910-A | Conjugates of dithiocarbamates with pharmacologically active agents and uses therefore | MEDINOX, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| EP-0866695-A1 | COMBINATIONAL THERAPEUTIC METHODS EMPLOYING NITRIC OXIDE SCAVENGERS | Medinox, Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| CN-1185781-A | Fused Polycyclic Heterocyclic Derivatives | EISAI CO LTD (JP) | 1998-06-24 | — | — | CN | disclosed |
| WO-1998009626-A1 | METHODS FOR IN VIVO REDUCTION OF IRON LEVELS AND COMPOSITIONS USEFUL THEREFOR | MEDINOX, INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| WO-1997018805-A1 | COMBINATIONAL THERAPEUTIC METHODS EMPLOYING NITRIC OXIDE SCAVENGERS | MEDINOX, INC. (US) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149430-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | MC2R, CYP11B2, NR3C2 | NOX1 2535/4885GAA 3874/4885MAPT 2671/4885 |
| US-20090311249-A1 | Capecitabine Combination Therapy | RICTOR, MTOR, EIF4E | NOX1 1265/4885GAA 2012/4885MAPT 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.