SCHEMBL29375737

SCHEMBL29375737

CC(=O)c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 13/20 1.00
▸ MAPT P10636 10/20 1.00
▸ GAA P10253 9/20 1.00
▸ MEN1 O00255 6/20 1.00
▸ KMT2A Q03164 6/20 1.00
▸ ALOX15 P16050 3/20 1.00
▸ SNCA P37840 2/20 1.00
▸ CYBB P04839 1/20 1.00
▸ APP P05067 1/20 1.00
▸ NOX3 Q9HBY0 1/20 1.00
▸ NOX4 Q9NPH5 1/20 1.00
▸ KCNH2 Q12809 1/20 0.62
▸ LMNA P02545 4/20 0.60
▸ NPSR1 Q6W5P4 3/20 0.60
▸ MAPK1 P28482 3/20 0.60
▸ POLB P06746 3/20 0.56
▸ L3MBTL1 Q9Y468 3/20 0.56
▸ NPC1 O15118 3/20 0.56
▸ RAB9A P51151 3/20 0.56
▸ KDM4E B2RXH2 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL28073776 1.00 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
SCHEMBL342449 1.00 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Ethylene SCHEMBL10370327 0.97 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
SCHEMBL12311060 0.90 NOX1 (0.82) NOX1MAPTGAAMEN1KMT2A
SCHEMBL3580166 0.85 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
SCHEMBL3586011 0.85 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
SCHEMBL31491519 0.85 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
SCHEMBL17284839 0.83 NOX1 (0.71) NOX1MAPTGAAMEN1KMT2A
SCHEMBL24220378 0.83 NOX1 (0.70) NOX1MAPTGAAMEN1KMT2A
SCHEMBL9778312 0.83 NOX1 (0.70) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 — — EP claimed
EP-4739298-A1 ACTIVATORS OF THE XC- SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION SORBONNE UNIVERSITE (FR) 2026-05-13 — — EP claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 — — WO claimed
EP-4205750-B1 NADPH OXIDASE INHIBITOR FOR SUPPRESSING OR IMPROVING HAIR LOSS OR TREATING ALOPECIA EADERM CO LTD (JP) 2025-04-09 — — EP claimed
US-12239655-B2 Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents EMORY UNIVERSITY (US) 2025-03-04 — — US claimed
WO-2025012667-A1 ACTIVATORS OF THE XC-SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION. SORBONNE UNIVERSITE (FR) 2025-01-16 — — WO claimed
WO-2025012137-A1 ACTIVATORS OF THE XC- SYSTEM AND/OR GPX-4 FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION SORBONNE UNIVERSITE (FR) 2025-01-16 — — WO claimed
CN-118079006-A Skin composition 国立大学法人东京医科齿科大学 2024-05-28 — — CN claimed
US-11814623-B2 Methods of treating a wound using epigenetic regulation UNIVERSITY OF MASSACHUSETTS (US) 2023-11-14 — — US claimed
EP-4205750-A1 COMPOSITIONS FOR SUPPRESSING OR IMPROVING HAIR LOSS AND GRAYING, AND USES THEREOF National University Corporation Tokyo Medical and Dental University (JP) 2023-07-05 — — EP claimed
US-20220331389-A1 SKIN COMPOSITION EADERM CO., LTD. (JP) 2022-10-20 — — US claimed
US-11298372-B2 Composition for ameliorating loss of hair and graying of hair, and use thereof NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2022-04-12 — — US claimed
EP-3978020-A1 SKIN COMPOSITION National University Corporation Tokyo Medical and Dental University (JP) 2022-04-06 — — EP claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 — — EP disclosed
EP-3856736-B1 NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2026-05-06 — — EP disclosed
US-12599660-B2 Therapeutic RNA for HPV-positive cancer BiòNTech SE (DE) 2026-04-14 — — US disclosed
EP-3978020-A1 SKIN COMPOSITION National University Corporation Tokyo Medical and Dental University (JP) 2022-04-06 — — EP disclosed
CN-114269378-A Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for the treatment of cancer 安斯泰来制药股份有限公司 2022-04-01 — — CN disclosed
CN-114026067-A Peptide mimetics for the treatment of coronavirus and picornavirus infections 埃默里大学 2022-02-08 — — CN disclosed
US-20220033379-A1 NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2022-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599660-B2 Therapeutic RNA for HPV-positive cancer UPF1, NSUN2, RNGTT NOX1 2369/4885MAPT 3225/4885GAA 3898/4885
US-12239655-B2 Combined modalities for nucleosides and/or NADPH oxidase (NOX) inhibitors as myeloid-specific antiviral agents NOX1, NOX3, NOX4 NOX1 1/4885MAPT 1860/4885GAA 901/4885
US-20220033379-A1 NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS CYBB, NOX1, NOX4 NOX1 2/4885MAPT 2492/4885GAA 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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