Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576786 | 0.78 | P2RX7 (0.50) | P2RX7LMNAPOLBEPHX2NR1H4 | |
| SCHEMBL5176812 | 0.78 | P2RX7 (0.57) | P2RX7EPHX2NR1H4 | |
| SCHEMBL3580858 | 0.77 | CA1 (0.48) | — | |
| SCHEMBL3235987 | 0.77 | BACE1 (0.60) | LMNARAB9A | |
| SCHEMBL5177106 | 0.75 | LMNA (0.51) | LMNAPOLBEPHX2NR1H4RAB9A | |
| SCHEMBL5178473 | 0.75 | P2RX7 (0.53) | P2RX7LMNAEPHX2NR1H4RAB9A | |
| SCHEMBL17240471 | 0.75 | RAB9A (0.55) | POLBRAB9A | |
| SCHEMBL26790250 | 0.74 | ADORA2A (0.49) | P2RX7LMNAPOLBRAB9A | |
| SCHEMBL3278159 | 0.74 | LMNA (0.68) | LMNAEPHX2NR1H4RAB9A | |
| SCHEMBL4159641 | 0.74 | KMT2A (0.69) | LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |