Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587299 | 0.84 | ALDH1A1 (0.38) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL22058063 | 0.82 | KDM4E (0.39) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL13384299 | 0.77 | FPR2 (0.35) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL15335292 | 0.72 | ALPL (0.47) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL3581217 | 0.72 | KDM4E (0.41) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL3591115 | 0.72 | CYP19A1 (0.45) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL16293127 | 0.71 | HDAC6 (0.40) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL29427431 | 0.71 | POLB (0.50) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL10553435 | 0.71 | FPR2 (0.51) | FPR2KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL21262137 | 0.70 | KDM4E (0.36) | FPR2KDM4EALDH1A1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | FPR2 64/4885KDM4E 3447/4885ALDH1A1 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.