Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584396 | 0.83 | C5AR1 (0.44) | POLBSERPINE1KMT2AMEN1KDM4E | |
| SCHEMBL3580741 | 0.83 | C5AR1 (0.40) | NPC1SERPINE1KMT2AMEN1KDM4E | |
| SCHEMBL3569982 | 0.81 | LPAR1 (0.41) | SERPINE1ALDH1A1MAPTCCR9GAA | |
| SCHEMBL3577656 | 0.80 | CNR1 (0.42) | RAB9ANPC1SERPINE1KMT2AMEN1 | |
| SCHEMBL3579634 | 0.80 | SERPINE1 (0.40) | SERPINE1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3569719 | 0.80 | SERPINE1 (0.40) | SERPINE1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3581193 | 0.80 | CCR9 (0.39) | SERPINE1KDM4EALDH1A1CCR9GAA | |
| SCHEMBL3575555 | 0.80 | F10 (0.42) | SERPINE1CCR9 | |
| SCHEMBL3584106 | 0.79 | LPAR1 (0.59) | SERPINE1LPAR1LPAR5LPAR2 | |
| SCHEMBL3583634 | 0.79 | SERPINE1 (0.39) | SERPINE1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |