Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581450 | 0.90 | MEP1B (0.41) | LPAR1LPAR5MEP1BMAPTTSHR | |
| SCHEMBL3575609 | 0.86 | LMNA (0.43) | LPAR1LPAR5SLC2A1C5AR1SMN1; SMN2 | |
| SCHEMBL3584396 | 0.85 | C5AR1 (0.44) | LPAR1LPAR5C5AR1GAASMN1; SMN2 | |
| SCHEMBL3580741 | 0.84 | C5AR1 (0.40) | LPAR1LPAR5C5AR1GAASMN1; SMN2 | |
| SCHEMBL3586145 | 0.84 | CNR1 (0.42) | LPAR1LPAR5SLC2A1C5AR1LPAR2 | |
| SCHEMBL3581404 | 0.84 | CNR1 (0.43) | LPAR1LPAR5C5AR1SERPINE1PPARG | |
| SCHEMBL3583813 | 0.84 | CNR1 (0.41) | LPAR1LPAR5C5AR1PPARGNR1H4 | |
| SCHEMBL3583634 | 0.83 | SERPINE1 (0.39) | MAPTC5AR1GAASMN1; SMN2SERPINE1 | |
| SCHEMBL3577812 | 0.83 | LPAR1 (0.43) | LPAR1LPAR5SLC2A1C5AR1LPAR2 | |
| SCHEMBL3576429 | 0.83 | LPAR1 (0.43) | LPAR1LPAR5TSHRSLC2A1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |