Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 11/20 | 0.34 |
| ▸ | CPT2 | P23786 | 5/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591381 | 0.92 | SCN9A (0.33) | CPT1ACPT2CPT1BSCN9ACCR5 | |
| SCHEMBL3587926 | 0.88 | SCN9A (0.33) | CPT1ACPT2CPT1BSCN9ACCR5 | |
| SCHEMBL3588558 | 0.84 | PTGS1 (0.37) | — | |
| SCHEMBL3590431 | 0.83 | EIF4E (0.37) | CPT1ACPT2KDM4EALDH1A1 | |
| SCHEMBL3634133 | 0.82 | CPT1A (0.31) | CPT1ACPT2SCN9A | |
| SCHEMBL3581546 | 0.81 | KDM4E (0.36) | CPT1ACPT2SCN9AKDM4EALDH1A1 | |
| SCHEMBL3591383 | 0.73 | ALDH1A1 (0.37) | SCN9AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3588041 | 0.70 | USP30 (0.38) | CPT1ACPT2CPT1BSCN9ACCR5 | |
| SCHEMBL3587927 | 0.69 | ALDH1A1 (0.38) | SCN9AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14496005 | 0.69 | L3MBTL1 (0.35) | SCN9AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | CPT1A 1947/4885CPT2 2552/4885CPT1B 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.