Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 3/20 | 0.35 |
| ▸ | TRPC7 | Q9HCX4 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587938 | 0.92 | GRIN2B (0.40) | ALDH1A1KDM4EHPGDHSD17B10TRPC3 | |
| SCHEMBL3590433 | 0.91 | TRPC3 (0.40) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3634136 | 0.91 | TRPC3 (0.34) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3591383 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3581546 | 0.88 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL2297608 | 0.87 | CCR5 (0.43) | ALDH1A1KDM4EHPGDHSD17B10SCN9A | |
| SCHEMBL3591327 | 0.87 | ENPP2 (0.41) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3586297 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10TRPC3 | |
| SCHEMBL3593203 | 0.86 | CPT1A (0.44) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3580394 | 0.85 | TRPC3 (0.44) | KDM4ETRPC3TRPC7ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | ALDH1A1 971/4885KDM4E 3447/4885HPGD 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.