Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.39 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3583196 | 0.99 | LMNA (0.41) | LMNAALDH1A1KDM4EHPGDSLC2A1 | |
| SCHEMBL3588212 | 0.92 | MAPT (0.36) | LMNAALDH1A1KDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3588209 | 0.91 | MCL1 (0.37) | LMNAALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL3594641 | 0.91 | MAPK1 (0.36) | LMNAALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL3584631 | 0.91 | MEN1 (0.42) | LMNAALDH1A1KDM4EHPGDSLC2A1 | |
| Hydrochloric Acid SCHEMBL3594638 | 0.90 | MCL1 (0.36) | LMNAALDH1A1KDM4EHPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL3584628 | 0.90 | MEN1 (0.42) | LMNAALDH1A1KDM4EHPGDSLC2A1 | |
| SCHEMBL3582540 | 0.89 | MCL1 (0.38) | LMNAALDH1A1KDM4ENPSR1MAPT | |
| Hydrochloric Acid SCHEMBL3582539 | 0.88 | MCL1 (0.40) | LMNAALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL3588704 | 0.87 | ALDH1A1 (0.35) | ALDH1A1NPSR1MAPTTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784403-B1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2013-07-17 | — | — | EP | claimed |
| US-7642269-B2 | Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2010-01-05 | — | — | US | claimed |
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2007-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213358-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, PPOX | LMNA 4407/4885ALDH1A1 1933/4885KDM4E 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.