Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581904 | 0.83 | HTR2C (0.47) | PTGER1CYP1A2CYP2C19 | |
| SCHEMBL3579000 | 0.82 | PTGER1 (0.50) | PTGER1LMNASMN1; SMN2 | |
| SCHEMBL3186878 | 0.79 | CYP1A2 (0.41) | PTGER1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL13693179 | 0.78 | PTGER1 (0.71) | PTGER1MEN1KMT2APKMCYP1A2 | |
| SCHEMBL3186195 | 0.77 | PTGDR2 (0.48) | PTGER1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL24797862 | 0.75 | PTGER1 (0.59) | PTGER1MEN1KMT2APKMCYP1A2 | |
| SCHEMBL3572631 | 0.75 | MEN1 (0.47) | PTGER1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL4803702 | 0.75 | NPBWR1 (0.50) | MEN1KMT2APKMALDH1A1GAA | |
| SCHEMBL29158354 | 0.75 | TLR7 (0.46) | MEN1KMT2APKMALDH1A1GAA | |
| SCHEMBL17627070 | 0.74 | KDM4E (0.56) | MEN1KMT2AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
| US-20100048617-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORP. | 2010-02-25 | — | — | US | disclosed |
| EP-2102188-A2 | COMPOUNDS | SmithKline Beecham Corporation (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008074833-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008074833-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048617-A1 | COMPOUNDS | SCD, SCD5, CYP11B2 | PTGER1 928/4885MEN1 3487/4885KMT2A 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.