Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002694 | 0.84 | TSHR (0.47) | NPBWR1ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL6003395 | 0.83 | P2RX3 (0.35) | NPBWR1TLR7ALDH1A1GAAMAPT | |
| SCHEMBL6002675 | 0.83 | TSHR (0.36) | ALDH1A1GAAMAPTTAAR1TSHR | |
| SCHEMBL4805719 | 0.80 | TSHR (0.53) | NPBWR1ALDH1A1MAPTIDO1TAAR1 | |
| SCHEMBL1491059 | 0.77 | NPBWR1 (0.48) | NPBWR1TLR7ALDH1A1GAAMAPT | |
| SCHEMBL4805694 | 0.76 | ALDH1A1 (0.56) | ALDH1A1GAAMEN1KMT2ATSHR | |
| SCHEMBL3583563 | 0.75 | PTGER1 (0.47) | ALDH1A1GAAMAPTIDO1TAAR1 | |
| SCHEMBL6003921 | 0.74 | TSHR (0.42) | NPBWR1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29158354 | 0.73 | TLR7 (0.46) | TLR7ALDH1A1GAAMAPTIDO1 | |
| SCHEMBL21523721 | 0.73 | MAPT (0.61) | ALDH1A1GAAMAPTIDO1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | claimed |
| EP-1313434-B1 | OXIDATION DYE | WELLA AG (DE) | 2005-01-12 | — | — | EP | claimed |
| US-6793687-B2 | YELLOW AND ORANGE RANGE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | claimed |
| US-20030159222-A1 | Oxidation dye | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-08-28 | — | — | US | claimed |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-17 | — | — | US | claimed |
| EP-1313434-A1 | OXIDATION DYE | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | claimed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | claimed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| US-7374583-B2 | Cationic azacyanine dyes and coloring agents containing said dyes | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070220685-A1 | Cationic azacyanine dyes and coloring agents containing said dyes | THE PROCTER & GAMBLE COMPANY (US) | 2007-09-27 | — | — | US | disclosed |
| EP-1802375-A1 | CATIONIC AZACYANINE DYES AND COLORANTS CONTAINING THESE | Wella Aktiengesellschaft (DE) | 2007-07-04 | — | — | EP | disclosed |
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2006042614-A1 | CATIONIC AZACYANINE DYES AND COLORANTS CONTAINING THESE | THE PROCTER & GAMBLE COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-17 | — | — | US | disclosed |
| EP-1313434-A1 | OXIDATION DYE | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | disclosed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159222-A1 | Oxidation dye | KRT18, NOX4, VIM | NPBWR1 4252/4885TLR7 3943/4885ALDH1A1 55/4885 |
| US-20070220685-A1 | Cationic azacyanine dyes and coloring agents containing said dyes | KRT18, DNMT1, NUP205 | NPBWR1 2755/4885TLR7 3994/4885ALDH1A1 1945/4885 |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | KRT18, AOC1, PPOX | NPBWR1 4354/4885TLR7 4271/4885ALDH1A1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.