Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579944 | 0.91 | MCHR1 (0.39) | MCHR1C5AR1CRHR1TACR1 | |
| SCHEMBL3576670 | 0.89 | MCHR1 (0.38) | MCHR1LMNACETPSLC2A1CRHR1 | |
| SCHEMBL3579477 | 0.88 | MCHR1 (0.37) | MCHR1KDM4ELMNAGAASLC2A1 | |
| SCHEMBL3569329 | 0.82 | C5AR1 (0.41) | C5AR1F10 | |
| SCHEMBL3574217 | 0.82 | MCHR1 (0.37) | MCHR1KDM4ELMNAGAASLC2A1 | |
| SCHEMBL3586536 | 0.81 | MCHR1 (0.37) | MCHR1LMNACETPTYRO3MERTK | |
| SCHEMBL3580209 | 0.81 | MCHR1 (0.40) | MCHR1CRHR1IRAK4 | |
| SCHEMBL3587988 | 0.81 | MCHR1 (0.39) | MCHR1KDM4ELMNAGAANLRP3 | |
| SCHEMBL3577776 | 0.79 | MCHR1 (0.37) | MCHR1NLRP3F2F10F7 | |
| SCHEMBL3576972 | 0.78 | BTK (0.36) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |